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February 28 – March 2

08:00 - 19:30

  • CAG Trainee Programs
  • CanHepC Meetings, by invitation only

** Session Recorded

Friday, March 3, 2023

  • 07:15 17:20

    CanHepC

    CanHepC

    Room 603/604

    7:15 - 8:00: CanHepC BREAKFAST

    8:00 - 8:15: CanHepC WELCOME & INTRODUCTIONS** - Christopher Richardson, Dalhousie University, Canada

    8:15 - 9:45: CanHepC SESSION 1**

    Biomedical Research – New Models and Innovation in Basic Hepatitis C Research, Diagnosis, Prevention, and Treatment

    Co-Chairs: Mohamed Abdel Hakeem, Emory University and Rodney Russell, Memorial University
    CanHepC trainees introducing plenary speakers: Jawairia Atif, University of Toronto and Simmone D’souza, University of Calgary

    • 8:15 - 8:35 Humanized mouse models for the study of HCV and other hepatotropic pathogens
      Alexander Ploss, Princeton University, USA

    • 8:35 - 8:55 miR-122 promotion of the HCV life cycle through time and space
      Joyce Wilson, University of Saskatchewan, Canada 

    • 8:55 - 9:15 Questions/Panel Discussion

    • 9:15 - 9:27 Activation Of Cd4 T Follicular Helper Cells Correlates With B Cell Expansion And Neutralizing Antibodies During HCV Reinfection And Clearance
      9:27 - 9:30 Q&A
      Elsa Guadalupe Gomez Escobar, CRCHUM

    • 9:30 - 9:42 Hedgehog Signalling Mediates CD8+ T-Cell Hyperfunction In Chronic HCV With Advanced Liver Fibrosis
      9:42 - 9:45 Q&A
      Jeff Li, University of Ottawa, Canada 

    9:45 - 10:00: AM BREAK & POSTER BROWSING (Exhibit Hall)

    10:00 - 11:30: CanHepC SESSION 2**

    Population Health Research – Novel Approaches to Track Progress towards HCV Elimination Targets

    Co-Chairs: Gisela Macphail, University of Calgary and Daniel Werb, University of Toronto
    CanHepC trainees introducing plenary speakers: Ana Maria Passos, McGill University and Jean Damascene Makuza, University of B.C.

    • 10:00 - 10:20 Importance of Structural Interventions for HCV Elimination Initiatives
      Peter Vickerman, University of Bristol, UK

    • 10:20 - 10:40 Health care utilization among PWID in three regions of Quebec: Preliminary findings from the Virtual Cascade of Care Cohort (VCCC) data linkage study
      Stine Hoj, Université de Montréal, Canada 

    • 10:40 - 11:00 Questions/Panel Discussion

    • 11:00 - 11:12 Incidence And Predictors Of Hepatitis C Outcomes In Immigrants And Non-Immigrants In Quebec, Canada: A Population-Based Study
      11:12 - 11:15 Q&A
      Ana Maria Passos-Castilho, McGill University, Canada

    • 11:15 - 11:27 The Population-Level Hepatitis C Care Cascade Among People Who Inject Drugs In Ontario Before And After The Introduction Of Direct-Acting Antiviral Therapy
      11:27 - 11:30 Q&A
      Zoë Greenwald, University of Toronto, Canada

    11:30 - 12:30: CanHepC COMMUNITY SESSION**

    Co-leaders: Renee Masching, Communities, Alliances and Networks (CAAN), Canada and Gerard Yetman, AIDS Committee of NL & Lab

    • Roadmaps for Engaging Living Experience in CanHepC 
      People with lived and living experience (also referred to as peers) bring insight and reality to research initiatives from the conception of a research idea to the completion of a research project. This panel of exceptional people will share insights about the “why” and “how” of peer engagement in research. From community-based research to patient-oriented care, the value of centring the people who we are trying to serve is essential.

      Moderator: Daryl Luster, BC Hepatitis Network

      Panellists: Sofia Bartlett, BC Centre for Disease Control
      Matthew Bonn,  Canadian Association of People Who Use Drugs
      Ashley Smoke, Northumberland Drug
      Katie Upham,  Substance User Network of the Atlantic Region (SUNAR) 

    12:30 - 14:00 LUNCH & POSTER SESSION (Exhibit Hall)

    • 13:00 - 13:45 CanHepC Poster Evaluation

    14:00 - 15:30 CanHepC SESSION 3**

    Clinical Research – HCV-positive Organ Transplant in HCV-Negative Recipients: Between Science and Reality

    Co-Chairs: Lisa Barrett, NSHA/Dalhousie University and Marc Bilodeau, Université de Montréal
    CanHepC trainees introducing plenary speakers: Mohamed Shengir, McGill University and Sasha Udhesister, Université de Montréal

    • 14:00 - 14:20  Changing landscape of organ transplantation from donors with hepatitis C 
      Christine Durand, John Hopkins University School of Medicine, USA

    • 14:20 - 14:40 Donor Derived Hepatitis C Infections: a Primer on Clinical Application
      Anouar Teriaky, Western University, Canada 

    • 14:40 - 15:00 Questions/Panel Discussion

    • 15:00 - 15:12 The Effect Of Metabolic Dysfunction-Associated Fatty Liver Disease On Liver Fibrosis Progression In HIV-Positive People With And Without Viral Hepatitis Coinfection: A Multicenter Longitudinal Study
      15:12 - 15:15 Q&A
      Giada Sebastiani, McGill University, Canada

    • 15:15 - 15:27 Optimizing Linkage To Hepatitis C Virus (HCV) Care For Untreated Individuals Released From Quebec Provincial Prison: Interim Analysis Of The Beyond Prison Walls Study
      15:27 - 15:30 Q&A
      Nadine Kronfli, McGill University, Canada

    15:30 - 17:00 CanHepC SESSION 4**

    Health System Services – Addressing the Burden of HCV Through Technical Solutions to Case-Finding

    Co-Chairs: Christina Greenaway, McGill University and Andrew Mendlowitz, University of Toronto  
    CanHepC trainees introducing plenary speakers: Guillaume Fontaine, University of Ottawa and Sameh Mortazhejri, University of Ottawa

    • 15:30 - 15:50 National Hepatitis C estimates: Incidence, prevalence, undiagnosed proportion and treatment, Canada, 2019
      Nashira Popovic, Public Health Agency of Canada, Canada

    • 15:50 - 16:10 Scale-up of Decentralised Point-of-Care Testing and Treatment for Hepatitis C Infection
      Jason Grebely, Kirby Institute - UNSW Sydney, Australia 

    • 16:10 - 16:30 Questions/Panel Discussion

    • 16:30 - 16:42 Estimating The Prevalence And Undiagnosed Proportion Of Chronic Hepatitis C Infection In Quebec Using Health Administrative Data
      16:42 - 16:45 Q&A
      Farinaz Forouzannia, University of Waterloo, Canada

    • 16:45 - 16:57 The First Provincial Correctional System-Wide Hepatitis C Care Cascade In Canada: Monitoring Hepatitis C Care In British Columbia Provincial Correctional Centres
      16:57 - 17:00 Q&A
      Sofia Bartlett,  BC Centre for Disease Control, Canada

    17:00 - 17:20 AWARDS & CLOSING REMARKS**

    • 17:00 - 17:10 CanHepC Trainee Awards Ceremony
      Nadine Kronfli, McGill University and Joyce Wilson, University of Saskatchewan

    • 17:10 - 17:20 Closing Remarks 
      Mia Biondi, York University
  • 07:50 20:00

    CANADIAN DIGESTIVE DISEASES WEEK™

    CDDW™

    8:00 - 9:30

    CLINICAL JOINT POSTGRADUATE COURSE** (Room C2/C3/C4)

    Foregut Neoplasia: From start to finish 

    Co-Chairs: Natalia Calo, The Ottawa Hospital, University of Ottawa & Michael Sey, London Health Sciences Centre

    • 8:00 - 8:25 Intestinal Metaplasia 
      Clarence Wong, University of Alberta
    • 8:25 - 8:50 Barrett's Esophagus
      Brian Yan, Western University
    • 8:50 - 9:15 Palliation of Obstruction
      Yen-I Chen, McGill University Health Centre
    • 9:15 - 9:30 Discussion 

    CLINICAL SYMPOSIUM** (Room 501/502)

    Quality Improvement

    Co-Chairs: David Armstrong, McMaster University & Adam Weizman, Mount Sinai Hospital, University of Toronto

    • 8:00 - 8:25 Quality Improvement in Endoscopy - What Has it Improved 
      Jill Tinmouth, Sunnybrook Health Sciences Center
    • 8:25 - 8:50 Quality Improvement Outside Endoscopy - An Untapped Well 
      Natasha Bollegala, Women's College Hospital, University of Toronto
    • 8:50 - 9:15 How to do Quality Improvement research
      Adam Weizman, Mount Sinai Hospital, University of Toronto 
    • 9:15 - 9:30 Discussion 

    BASIC SCIENCE SYMPOSIUM** (Room 506/507)

    The Eukaryome in Intestinal Health and Disease

    Co-Chairs: Arthur Mortha, University of Toronto & Lisa Osborne, University of British Columbia

    • 8:00 - 8:20 Host-Mycobiota Interactions 
      Rebecca Shapiro, University of Guelph
    • 8:20 - 8:40 Helminths/worms 
      Lisa Reynolds, University of Victoria
    • 8:40 - 9:00 Protozoa of the Gut Eukaryome: From trans-kingdom communications to drug targets
      Andre Buret, University of Calgary
    • 9:00 - 9:15 Early-Life Fungal Colonization Mediates Host Metabolism And White Adipose Tissue Inflammation In Mice
      Mackenzie W. Gutierrez, University of Calgary
    • 9:15 - 9:30 Discussion 

    9:30 - 10:00 AM BREAK & POSTER BROWSING (Exhibit Hall)

    10:00 - 11:30

    CLINICAL POSTGRADUATE COURSE** (Room C2/C3/C4)

    What's New in IBD

    Co-Chairs: Jeffrey McCurdy, University of Ottawa & Laura Targownik, University of Toronto

    • 10:00 - 10:25 IBD in Pregnancy - What the General GI Needs to Know
      Vivian Huang, Mount Sinai Hospital/University of Toronto
    • 10:25 - 10:50 Transition in IBD - How to Make Your Patients Feel Safe 
      Anthony Otley, IWK Health Centre/Dalhousie University
    • 10:50 - 11:15 Landmark Paradigm Shifts in IBD Therapy: An Evolving Journey 
      Jeffrey McCurdy, University of Ottawa
    • 11:15 - 11:30 Discussion

    SMALL GROUP  (Argyle Suite)

    Case-Based Discussion on Common Endoscopic and Therapeutic Procedures (SOLD OUT)

    STATIONS

    Under the supervision of Alaa Rostom, University of Ottawa

    • Polypectomy (Video based discussion)
      Eric Greenwald, McMaster University
      Jeffrey Mosko, University of Toronto

    • Hemostasis (Video based discussion)
      Mark Borgaonkar, Memorial University
      Dana Farina, Dalhousie University

    • SEE™ Station 1 (Demo with Equipment)
      Kevin Waschke, McGill University

    • SEE™ Station 2 (Demo with Equipment)
      Donald MacIntosh, Dalhousie University

    • Video Capsule Endoscopy
      Robert Berger, Dalhousie University

    BASIC SCIENCE PAPER SESSION** (Room 506/507)

    CAG Student Prize Paper Presentations

    Co-Chairs: Wallace MacNaughton, University of Calgary & Nathalie Perreault, Université de Sherbrooke

    • 10:00 - 10:10 Targeting Il-4 And Il-13 To Treat Crohn’s Disease-Associated Intestinal Fibrosis In Ship Deficient Mice
      10:10 - 10:15 Q&A
      Kwestan Safari, University of British Columbia
    • 10:15 - 10:25 Acute Colitis Causes Changes to the Efficacy Of Cannabinoid-1 And Mu-Opioid Receptor Agonists On Inhibiting Abdominal Pain
      10:25 - 10:30 Q&A
      Quentin K. Tsang, Queen's University
    • 10:30 - 10:40 Crohn’s Disease Proteolytic Microbiota Enhances Inflammation Through Par2 Pathway In Gnotobiotic Mice
      10:40 - 10:45 Q&A
      Amber Hann, McMaster University

    • 10:45 - 10:55 Prednisolone, A Glucocorticoid Widely Used For Treatment of IBD, Enhances A Human Interleukin-4-Activated Macrophage Phenotype
      10:55 - 11:00 Q&A
      Rujuta Shailesh Deshpande, University Of Calgary

    • 11:00 - 11:10 Protease-Activated Receptor (Par)-2 Activation Enhances Epithelial Wound Healing Migration Through Src And Rac1 Pathways
      11:10 - 11:15 Q&A
      Larissa Lucena Perico, University Of Calgary

    • 11:15 - 11:25 Opportunistic Pathogen Modulation Of Gluten-Reactive Cd4+ T Cell Activation By Dq2-Expressing Organoid Monolayers
      11:25 - 11:30 Q&A
      Sara Rahmani, McMaster University

    11:30 - 12:30 LUNCH BREAK (Exhibit Hall)

    12:30 - 14:30

    CLINICAL POSTGRADUATE COURSE** (Room C2/C3/C4)

    Functional Gastrointestinal Disease

    Co-Chairs: Adriana Lazerescu, University of Alberta & David Rodrigues, Queen's University

    • 12:30 - 13:00 Functional Dyspepsia 
      Nicholas Talley, Newcastle University
    • 13:00 - 13:30 IBS: Too fast or too slow, what’s new in treatments for IBS.
      Yasmin Nasser, University of Calgary
    • 13:30 - 14:00 Small Intestinal Bacteria Overgrowth: What role does it have in GI disease?
      Stephen Vanner, Queen's University
    • 14:00 - 14:30 Discussion 

    SMALL GROUP (Argyle Suite)

    Case-Based Discussion on Common Endoscopic and Therapeutic Procedures (SOLD OUT)

    STATIONS

    Under the supervision of Alaa Rostom, University of Ottawa

    • Polypectomy (Video based discussion)
      Eric Greenwald, McMaster University
      Jeffrey Mosko, University of Toronto

    • Hemostasis (Video based discussion)
      Mark Borgaonkar, Memorial University
      Dana Farina, Dalhousie University

    • SEE™ Station 1 (Demo with Equipment)
      Kevin Waschke, McGill University

    • SEE™ Station 2 (Demo with Equipment)
      Donald MacIntosh, Dalhousie University

    • Video Capsule Endoscopy
      Robert Berger, Dalhousie University

    BASIC SCIENCE SYMPOSIUM** (Room 506/507)

    Mechanisms Involving the Epithelial Barrier

    Co-Chairs: François Boudreau, Université de Sherbrooke & Laura Sly, University of British Columbia

    • 12:30 - 12:55 NOD2 at the Interface of Bacterial Sensing and Epithelial Barrier 
      Dana Philpott, University of Toronto
    • 12:55 - 13:20 Clock Gene and Epithelial Permeability 
      Phillip Karpowicz, University of Windsor
    • 13:20 - 13:45 The Mucus as a Barrier
      Kirk Bergstrom, University of British Columbia
    • 13:45 - 14:00 Genetic Or Diet-Associated Defects In Mucus Facilitate Ulcerative Colitis Pathobiont-Driven Colitis.
      Hyungjun Yang, University of Calgary 
    • 14:00 - 14:30 Discussion

    14:30 - 15:00 PM BREAK & POSTER BROWSING (Exhibit Hall)

    15:00 - 16:30

    CLINICAL POSTGRADUATE COURSE** (Room C2/C3/C4)

    What's New in Acute Pancreatitis

    Co-Chairs: Lawrence Hookey, Queen’s University & Jeffrey Mosko, St. Michael's Hospital

    • 15:00 - 15:25 Surgery in Acute Pancreatitis: What role in current day practice?
      Mark Walsh, Dalhousie University
    • 15:25 - 15:50 Complications of Acute Pancreatitis 
      Gary May, University of Toronto
    • 15:50 - 16:15 What's New in Gallstone Pancreatitis 
      Jennifer Telford, University of British Columbia
    • 16:15 - 16:30 Discussion 

    CLINICAL SYMPOSIUM: NASPGHAN** (Room 501/502)

    Health Equity and Social Determinants of Health in Clinical Care and Research of Children with Digestive Disease

    Chair: Nicola Jones, SickKids

    • 15:00 - 15:25 Diversity in Pediatric Gastroenterology: How do we change
      Conrad Cole, Cincinnati Children's Hospital Medical Center
    • 15:25 - 15:50 Social Determinants of Health and Implicit Bias: How Both Affect Patient Care
      Valeria Cohran, The Ann & Robert H. Lurie Children's Hospital of Chicago
    • 15:50 - 16:15 Working with Indigenous patient and family advocates for better access to specialized care for Indigenous individuals with inflammatory bowel disease: experiences and perspectives from Saskatchewan, Canada
      Juan-Nicolas Pena-Sanchez, University of Saskatchewan
      Linda Porter, Indigenous patient-family partner

    • 16:15 - 16:30 Discussion

    BASIC SCIENCE SYMPOSIUM** (Room 506/507)

    What's New on the Frontline of Endocrine Regulations in the GI Tract?

    Co-Chairs: Jean-Eric Ghia, University of Manitoba & Waliul Khan, McMaster University

    • 15:00 - 15:20 Enterchromaffin cells and chromogranin A 
      Jean-Eric Ghia, University of Manitoba
    • 15:20 - 15:40 Tuft Cells 
      Derek McKay, University of Calgary
    • 15:40 - 16:00 Endocrines Peptides
      Ravinder K. Gill, University of Illinois
    • 16:00 - 16:15 A Mouse Model To Unravel The Pathophysiological Link Between Crohn’s Disease And Type-2 Diabetes-Associated Metabolic Disorders 
      Tapas Mukherjee, University of Toronto

     

     

     

     

     

     

     

     

     

    16:30 17:30 CAG AGM (For CAG Members Only - Room 501/502)

    17:30 - 18:30 CAG OPENING RECEPTION (Exhibit Hall)

    18:30 - 20:00 CAG POSTER SESSION 1 (Exhibit Hall)

    Esophageal, Gastric & Duodenal Disorders
    Inflammatory Bowel Disease: Mechanisms & Treatments
    Intestinal Disorders
    Microbiome & Microbial Therapy
    Neurogastroenterology & Motility
    Pancreatic Disorders

  • 08:30 16:30

    CanNASH

    CanNASH

    Room 608/609

    7:15 - 8:30 CanNASH BREAKFAST

    8:30 - 8:40 CanNASH OPENING REMARKS**
    Giada Sebastiani, Workshop Chair, McGill University & Keyur Patel, University Health Network

    8:40 - 10:10 CanNASH SESSION 1**

    Epidemiology and Natural History 

    Co-Moderators: Alnoor Ramji, University of British Columbia and Wendy Schaufert, Canadian Association of Hepatology Nurses

    • 8:40 - 9:00 Global epidemiology of NASH
      Mohamed Eslam, University of Sydney, Australia (Virtual Presentation)
    • 9:00 - 9:20 Cardiovascular outcomes in NASH
      Paolo Raggi, University of Alberta
    • 9:20 - 9:40 Key metabolic factors driving the natural history of NAFLD  
      Harpreet Bajaj, Mount Sinai Hospital
    • 9:40 - 9:52 Machine Learning Using Simple Non-Invasive Tests of Fibrosis & B-Mode Ultrasound for the Prediction of Adverse Liver-Related Outcomes in NAFLD – A Multicentre Validation Study
      Heather Mary-Kathleen Kosick
    • 9:52 - 10:10 Q&A

    10:10 - 10:30 AM BREAK & POSTER BROWSING (Exhibit Hall)

    10:30 - 12:00 CanNASH SESSION 2**

    Diagnostics

    Co-Moderators: Angela Crawley, University of Ottawa and Magnus McLeod, Dalhouise University

    • 10:30 - 10:50 Guidelines on NAFLD diagnostics
      Annalisa Berzigotti, University of Bern, Switzerland (Virtual Presentation)
    • 10:50 - 11:10 Clinical pathways for NAFLD
      Mark Swain, University of Calgary
    • 11:10 - 11:30 The future: new biomarkers for NASH and fibrosis
      Massimo Pinzani, University College of London, UK
    • 11:30 - 11:42 Risk-Stratification of Patients with Non-Alcoholic Fatty Liver Disease (NAFLD): Lessons from the Calgary NAFLD Pathway
      Abdel Aziz Shaheen, University of Calgary
    • 11:42 - 12:00 Q&A

    12:00 - 13:00 LUNCH & POSTER SESSION (Exhibit Hall)

    13:00 - 14:30 CanNASH SESSION 3**

    Public Health and Policy

    Co-Moderators: Michael Betel, Fatty Liver Alliance and Sahar Saeed, Queen’s University

    • 13:00 - 13:20 Patient lived experience with NASH, diabetes and liver transplant
      Heather Watson, Edmonton, AB
    • 13:20 - 13:40 Screening in at risk populations
      Grace Wong, Chinese University of Hong Kong (Virtual Presentation)
    • 13:40 - 14:00 The Projected Economic Impact of NALFD in Canada
      Fiona Clements, University of Calgary (Virtual Presentation)
    • 14:00 - 14:12 Significance of Non-Alcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis in Population Screening with Vibration Controlled Transient Elastography: Liver Beware Project
      Harjot Bedi,University of British Columbia
    • 14:12 - 14:30 Q&A

    14:30 - 14:50 PM BREAK & POSTER BROWSING (Exhibit Hall)

    14:50 - 16:20 CanNASH SESSION 4**

    Therapeutics

    Co-Moderators: Kaberi Dasgupta, McGill University & Abdel Aziz Shaheen, University of Calgary

    • 14:50 - 15:10 Diet and Nutrition Updates in the management of NAFLD
      Maitreyi Raman, University of Calgary
    • 15:10 - 15:30 Diabetic Pharmacotherapy for NASH
      Kenneth Cusi, University of Florida, USA (Virtual Presentation)
    • 15:30 - 15:50 Perspective on antifibrotic NASH studies
      Manal Abdelmalek, Mayo Clinic (Virtual Presentation)
    • 15:50 - 16:02 Nuclear Factor Erythroid 2 Related Factor-1 And -2 Co-Guard Against Cholesterol-Associated Steatohepatitis
      May Akl, University of Saskatchewan
    • 16:02- 16:20 Q&A & Discussion

    16:20 - 16:30 CanNASH CLOSING REMARKS AND FUTURE DIRECTIONS**
    Mark Swain, President of the Canadian Association for the Study of the Liver, University of Calgary

  • 17:20 18:15

    CANADIAN LIVER MEETING

    CanHepC - Canadian Network on Hepatitis C

    Room 603/604

     

    17:20 - 17:30 CANADIAN LIVER MEETING OPENING REMARKS**
    Mark Swain, President of the Canadian Association for the Study of the Liver, University of Calgary

    17:30 - 18:00 CASL AWARDS CEREMONY**

    18:00 - 18:15 CLF-CASL Gold Medal Lecture** introduced by Jennifer Nebesky, Canandian Liver Foundation

    18:15 - 18:45 A Journey Through the Life of a Hepatology Lucky Boy by Marc Bilodeau, Université de Montréal

    18:45 20:30 CLM OPENING RECEPTION & CASL‑CANHEPC‑CANNASH POSTERS (Exhibit Hall)